赵晓宇，博士
上海市浦江人才
上海感染与免疫科技创新中心PI
复旦大学感染与健康研究院青年研究员
【研究方向】
针对RNA病毒的中和抗体及药物筛选
系统性评估预防性疫苗和抗体的保护效力
新发突发RNA病毒与宿主相互作用的机制研究
【研究成果】
2021年获得香港大学博士学位，并于同年进入复旦大学开展博士后研究，2024年起担任研究院青年研究员。累计发表SCI论文40余篇，其中以第一作者或通讯作者（含共同）在Cell Host & Microbe、Cell Discovery、Nature Communications、EBioMedicine、Emerging Microbes & Infections、Journal of Virology、MedComm、Nature Reviews Immunology等国际权威期刊上发表学术论文16篇。
主持国家自然科学基金青年项目和上海市白玉兰人才计划浦江项目，并作为骨干成员参与国家重点研发计划和上海高水平地方高校创新团队等重大科研项目。入选复旦大学“超级博士后”计划、2022年博士后国际交流计划引进项目、2023年上海市浦江人才计划等人才激励计划，并荣获2022年度“谈家桢博士后学者奖”一等奖等荣誉。
【学术兼职】
担任上海市药学会生化与生物技术药物专业委员会青年委员，以及Virology Journal和Frontiers in Virology期刊的Associate Editor、Frontiers in Immunology期刊的Guest Editor以及Scientific Reports期刊的编委会成员。
【发表论文（部分）】
第一作者（*）/通讯作者（#）（含共同）
1. Xiaoyu Zhao, Hin Chu. Decoding broadly neutralizing antibodies: a milestone in SFTSV therapy. EBioMedicine, 2025.
2. Xiaoyu Zhao (#), Rui Qiao, Meng Hao, Longfa Xu, Dong Wang, Yinying Lu, Jiayan Li, Jing Wu, Yi Li, Tong Cheng, Wenhong Zhang, Jincun Zhao (#), Pengfei Wang (#). Vascular endothelial growth factor receptor 2 as a potential host target for the inhibition of enterovirus replication. Journal of Virology, 2024.
3. Xiaoyu Zhao, Tianyi Qiu, Xiner Huang, Qiyu Mao, Yajie Wang, Rui Qiao, Tiantian Mao, Yuan Wang, Jiayan Li, Cuiting Luo, Chaemin Yoon, Xun Wang, Chen Li, Yuchen Cui, Chaoyue Zhao, Minghui Li, Yanjia Chen, Guonan Cai, Wenye Geng, Zixin Hu, Jinglei Cao, Wenhong Zhang, Zhiwei Cao, Hin Chu, Lei Sun, Pengfei Wang. Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination. Cell Discovery, 2024.
4. Yuanchen Liu*, Xiaoyu Zhao*, Jialu Shi*, Yajie Wang, Huan Liu, Yefan Hu, Bingjie Hu, Huiping Shuai, Terrence Tsz-Tai Yuen, Yue Chai, Feifei Liu, Huarui Gong, Jiayan Li, Xun Wang, Shujun Jiang, Xiang Zhang, Yanliang Zhang, Xiangnan Li, Lei Wang, Madeline Hartnoll, Tianrenzheng Zhu, Yuxin Hou, Xiner Huang, Chaemin Yoon, Yang Wang, Yixin He, Minmin Zhou, Lianzhao Du, Xiaojuan Zhang, Wanmui Chan, Linlei Chen, Jianpiao Cai, Shuofeng Yuan, Jie Zhou, Jiandong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Baozhong Zhang, Lei Sun, Pengfei Wang, Hin Chu. Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3. Nature Communications, 2024.
5. Yanjia Chen*, Xiaoyu Zhao*, Hao Zhou*, Huanzhang Zhu, Shibo Jiang, Pengfei Wang. Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses. Nature Reviews Immunology, 2023.
6. Xiaoyu Zhao, Cun Li, Man Chun Chiu, Rui Qiao, Shibo Jiang, Pengfei Wang, Jie Zhou. Rock1 is a novel host dependency factor of human enterovirus A71: Implication as a drug target. Journal of Medical Virology, 2022.
7. Xiaoyu Zhao, Cun Li, Xiaojuan Liu, Man Chun Chiu, Dong Wang, Yuxuan Wei, Hin Chu, Jian-Piao Cai, Ivy Hau-Yee Chan, Kenneth Kak-Yuen Wong, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Kwok Yung Yuen and Jie Zhou. Human intestinal organoids recapitulate enteric infections of enterovirus and coronavirus. Stem Cell Reports, 2021.
8. Xiaoyu Zhao, Hin Chu, Bosco Ho-Yin Wong, Man Chun Chiu, Dong Wang, Cun Li, Xiaojuan Liu, Dong Yang, Vincent Kwok-Man Poon, Jianpiao Cai, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Jie Zhou, Kwok-Yung Yuen. Activation of C-Type lectin receptor and (RIG)-I-Like receptors contributes to proinflammatory response in Middle East Respiratory Syndrome Coronavirus-infected macrophages. The Journal of Infectious Diseases, 2020.
