【教育经历】
2003.09-2007.09，四川大学，生物技术，本科
2007.09-2013.07，中国科学院大学，发育生物学，博士
【工作经历】
2013.12-2014.07，中国科学院大学，研究助理
2014.07-2019.11，爱丁堡大学，博士后
2019.12-2021.04，生物岛实验室，研究员
2021.05至今，广州实验室，研究员
【研究简介】
2007年毕业于四川大学生物技术专业，获学士学位。同年进入中国科学院上海生物化学与细胞生物学研究所攻读博士，于2013年获发育生物学博士学位。2014年7月至2019年11月期间在爱丁堡大学从事博士后研究；2019年12月起任生物岛实验室细胞命运与谱系研究中心研究员。2021年加入广州实验室担任研究员，从事干细胞和呼吸系统再生研究。目前获国家海外高层次人才（青年项目），国自然面上基金等支持。目前以通讯作者、第一作者或共同第一作者身份在Nature, Cell Research, Developmental Cell, Cell Reports等权威杂志上发表学术论文多篇。
【人才头衔与荣誉奖励】
1. 广州市优秀专家
2. 国家重大人才项目入选者（青年）
【代表性成果】
1. Zhang P.*, Zhai X.*, Huang B.*, Sun S., Wang W., Zhang M. 2023, Highly efficient generation of blastocyst-like structures from spliceosomes-repressed mouse totipotent blastomere-like cells, Sci China Life Sci.1674-7305.
2. Vojtek, M., Zhang, J., Sun, J., Zhang, M. #, & Chambers, I#. 2022, Differential repression of Otx2 underlies the capacity of NANOG and ESRRB to induce germline entry, Stem cell reports, 17(1): 35-42. (#, co-corresponding author)
3. Yu S*, Zhou C*, He J*, Yao Z, Huang X, Rong B, Zhu H, Wang S, Chen S, Wang X, Cai B, Zhao G, Chen Y, Xiao L, Liu H, Qin Y, Guo J, Wu H, Zhang Z, Zhang M, Zhao X, Lan F, Wang Y, Chen J, Cao S, Pei D, Liu J. BMP4 drives primed to naïve transition through PGC-like state, 2022, Nat Communications, 19;13(1):2756 (*, co-first author)
4. Liu, J., Gao, M., He, J., Wu, K., Lin, S., Jin, L., Chen, Y., Liu, H., Shi, J., Wang, X., Chang, L.，Lin, Y.，Zhao, Y. L.，Zhang, X.，Zhang, M.，Luo, G. Z.，Wu, G.，Pei, D.，Wang, J.，Bao, X.，Chen, J. 2021, The RNA m(6)A reader YTHDC1 silences, retrotransposons and guards ES cell identity Nature, 591, 322-326.
5. Zhang, JC*., Zhang, M* #., Acampora D., Vojtek M., Yuan DT., Simeone, A., Chambers I#, 2018, Otx2 restricts entry to the mouse germline, Nature. 562 (7728), 595-599, 2018 (*, co-first author, #, co-corresponding author).
6. Zhang, M., Leitch, H.G., Tang, W.W.C., Festuccia, N., Hall-Ponsele, E., Nichols, J., Surani, M.A., Smith, A., and Chambers, I. , 2018, Esrrb Complementation Rescues Development of Nanog -Null Germ Cells, Cell Reports, 22, 332-339.
7. Barakat, T.S., Halbritter, F., Zhang, M., Rendeiro, A.F., Perenthaler, E., Bock, C., and Chambers, I., 2018, Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells, Cell Stem Cell, 23, 276-288 e278.
8. Gou, L.T., Kang, J.Y., Dai, P., Wang, X., Li, F., Zhao, S., Zhang, M., Hua, M.M., Lu, Y., Zhu, Y., et al., 2017, Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis, Cell, 169, 1090-1104 e1013.
9. Wu, Y*., Zhou, H*., Fan, X*., Zhang, Y*., Zhang, M*., Wang, Y., Xie, Z., Bai, M., Yin, Q., Liang, D., Tang, W., Liao, J., Zhou, C., Liu, W., Zhu, P., Guo, H., Pan, H., Wu, C., Shi, H., Wu, LG., Tang, FC., Li, JS., 2015, Correction of a genetic disease by CRISPR Cas9-mediated gene editing in mouse spermatogonial stem cells, Cell Research, 25, 67-79. (*, co-first author)
10. Zhang, M., Zhou, H., Zheng, C., Xiao, J., Zuo, E., Liu, W., Xie, D., Shi, Y., Wu, C., Wang, H., Li, DS., Li, JS., 2014, The roles of testicular c-kit positive cells in de novo morphogenesis of testis, Scientific Reports, 4, 5936.
